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Study identifier: NCT06762977 Synced from ClinicalTrials.gov · July 28, 2026
● Recruiting

A Composite Assay for HER2-positive Early-stage Breast Cancer Management

Condition: Breast Cancer Early Stage Breast Cancer (Stage 1-3) · HER2  ·  Sponsor: Fondazione IRCCS Istituto Nazionale dei Tumori, Milano

PhaseN/A
Planned participants180
Who can joinAll sexes, 18 Years to no upper limit
Healthy volunteersNo

About this study

The goal of this observational study is to assess the prognostic value of a genomic classifier (S18) and its refined version (S\*) in women with early-stage HER2-positive breast cancer. The study aims to determine whether these tools can predict event-free (EFS) and disease-free survival (DFS) in patients treated with neoadjuvant and/or adjuvant trastuzumab-based therapies.

This description comes directly from the study's public registry record.

Talk to the study team

Serena Di Cosimo, MD, PhD  ·  +39 02 2390 2700  ·  serena.dicosimo@istitutotumori.mi.it

Paolo Verderio, PhD  ·  +39 02 2390 3201  ·  paolo.verderio@istitutotumori.mi.it

Always discuss trial participation with your own doctor first.

Locations (2)

Ospedale Di Summa-PerrinoBrindisi, ItalyRecruiting
Istituto Nazionale Tumori IRCCS - Fondazione G. PascaleNaples, ItalyRecruiting

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Source record: clinicaltrials.gov/study/NCT06762977