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Study identifier: NCT06762795 Synced from ClinicalTrials.gov · July 29, 2026
● Recruiting

The HIEnome Study: Genome Sequencing for Perinatal HIE

Condition: Hypoxic Ischemic Encephalopathy of Newborn · Hypoxic Ischemic Encephalopathy · Hypoxic Ischemic Encephalopathy (HIE)  ·  Sponsor: Baylor College of Medicine

PhaseNA
Planned participants25
Who can joinAll sexes, 0 Days to 1 Year
Healthy volunteersNo

About this study

Perinatal hypoxic-ischemic encephalopathy is a rare severe condition in which neonates present with encephalopathy and a clinical history suggestive of prenatal or perinatal hypoxic-ischemic injury. Emerging evidence suggests that genetic conditions are frequently identified in cases of perinatal HIE; however, it is unclear which neonates with this diagnosis warrant genetic testing. This study will offer clinical genome sequencing to neonates with HIE who are undergoing total body cooling (therapeutic hypothermia) and their parents.

This description comes directly from the study's public registry record.

Talk to the study team

Christian Parobek, MD, PhD  ·  828-713-9962  ·  christian.parobek@bcm.edu

Seema Lalani, MD  ·  7137988921  ·  seemal@bcm.edu

Always discuss trial participation with your own doctor first.

Locations (2)

Texas Children's HospitalHouston, Texas, United StatesRecruiting
Texas Children's HospitalHouston, Texas, United StatesRecruiting

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Source record: clinicaltrials.gov/study/NCT06762795