Condition: Hypothalamic Obesity · Multiple Pituitary Hormone Deficiency Genetic Form · Septo-Optic Dysplasia · Sponsor: Rhythm Pharmaceuticals, Inc.
This is a sub-study of Study RM-493-040 (NCT05774756). The goal of this sub-study is to learn how well Setmelanotide works to improve weight reduction, hunger, and quality of life in patients 4 years of age and older with congenital Hypothalamic Obesity (cHO). To determine how well setmelanotide works and how safe it is, patients with cHO will take a daily injection of either setmelanotide or placebo and complete trial assessments for up to 26 weeks on a therapeutic regimen.
This description comes directly from the study's public registry record.
Rhythm Clinical Trials · (857) 264-4280 · clinicaltrials@rhythmtx.com
Physician Inquiry Clinical Trials · (857) 264-4280 · clinicaltrials@rhythmtx.com
Always discuss trial participation with your own doctor first.
| University of Alabama | Birmingham, Alabama, United States | Recruiting |
| Children's Hospital Colorado | Aurora, Colorado, United States | Recruiting |
| Lurie Children's Hospital | Chicago, Illinois, United States | Recruiting |
| Boston Children's Hospital | Boston, Massachusetts, United States | Recruiting |
| Children's Minnesota | Saint Paul, Minnesota, United States | Recruiting |
| Columbia University Irving Medical Center | New York, New York, United States | Recruiting |
| Children's Hospital of Philadelphia | Philadelphia, Pennsylvania, United States | Recruiting |
| Seattle Children's Research Institute | Seattle, Washington, United States | Recruiting |
| UCL Great Ormond Street Institute of Child Health | London, Greater London, United Kingdom | Recruiting |
| Birmingham Women and Children's Hospital NHS Trust | Birmingham, West Midlands, United Kingdom | Recruiting |
| Hull Royal Infirmary | Hull, United Kingdom | Recruiting |
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Source record: clinicaltrials.gov/study/NCT06760546