Condition: Obesity and Overweight · Sponsor: Associação Centro de Apoio Tecnológico Agro Alimentar
Kombucha, a fermented beverage made from Camellia sinensis tea (black, oolong, or green) with sugar and a symbiotic culture of bacteria and yeast (SCOBY), has gained global attention for its potential health benefits. Factors like the type and amount of sugar substrate, fermentation time, and temperature significantly influence its organic compounds, total phenolics, vitamin content, and alcohol levels. In a previous study, kombucha's impact on glucose tolerance, insulin sensitivity, body composition, and liver function was tested in male prediabetic mice with diet-induced obesity. Daily supplementation (200 µL per mouse) improved glucose tolerance after nine days (equivalent to one year in humans) and reduced liver steatosis, despite no changes in body composition. Although kombucha has been associated with antioxidant, antimicrobial, probiotic, antidiabetic, and anticancer activities, strong scientific evidence in humans remains limited. Further clinical studies are needed to substantiate kombucha's health benefits in humans.
This description comes directly from the study's public registry record.
Inês Brandão, PhD · +351926777221 · inesbrandao@cataa.pt
Filomena Pereira, Nutritionist · filomenapereira@cataa.pt
Always discuss trial participation with your own doctor first.
| Centro de Apoio Tecnológico Agro Alimentar (CATAA) | Castelo Branco, Castelo Branco District, Portugal | Recruiting |
| Centro de Apoio Tecnológico Agro Alimentar (CATAA) (facilities temporarily provided by the Affidea clinical analysis center) | Covilha, Portugal | Recruiting |
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Source record: clinicaltrials.gov/study/NCT06759324