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Study identifier: NCT06758115 Synced from ClinicalTrials.gov · July 28, 2026
● Recruiting

Central Motor Mechanisms in AIS Via HD-sEMG, EEG and Neuromuscular Coupling Analysis

Condition: Adolescent Idiopathic Scoliosis  ·  Sponsor: The First Affiliated Hospital of Zhejiang Chinese Medical University

PhaseN/A
Planned participants40
Who can joinAll sexes, 10 Years to 18 Years
Healthy volunteersYes

About this study

1. Verifying the Motor Control Effects of Spinal Manipulation on AIS Using outpatient and inpatient AIS patients from our department as the study subjects, standardized spinal manipulation treatment is applied. The efficacy is evaluated through a combination of clinical outcome measures, HD-EMG for paraspinal muscle function assessment, and Pro-Kin balance system for trunk stability analysis. This establishes an AIS efficacy platform to further clarify the effectiveness of spinal manipulation in motor control regulation of AIS. 2. Investigating the Central Motor Network's Response to Spinal Manipulation in AIS Utilizing high-density sEMG-EEG technology, synchronized brain and muscle electrical signals are collected before and after treatment. By employing a neuromuscular synchronization and coupling analysis approach that integrates linear and nonlinear methods, the characteristic indices of information interaction between the central system and muscles are identified. This further explores the motor control and response characteristics of the muscle-cortex network to spinal manipulation in AIS.

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Locations (1)

the First Affiliated Hospital of Zhejiang Chinese Medical UniversityHangzhou, ChinaRecruiting

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Source record: clinicaltrials.gov/study/NCT06758115