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Study identifier: NCT06757569 Synced from ClinicalTrials.gov · July 28, 2026
● Recruiting

Radialis PET Imager for the Assessment of Neuritic Amyloid Plaque Burden

Condition: Cognitive Impairment  ·  Sponsor: University Health Network, Toronto

PhaseNA
Planned participants160
Who can joinAll sexes, 18 Years to no upper limit
Healthy volunteersNo

About this study

The standard or usual workup for cognitive impairment, including Alzheimer's Disease, may include brain amyloid PET with PET/CT or PET/MR imaging. Amyloid PET is the standard imaging that was requested for you by your referring physician. This imaging can visualize your brain. With the development of new therapies for Alzheimer's disease which require amyloid PET imaging, there will be a significant increase in the number of PET scans needed to provide care to all patients. There are likely not enough PET scanners in Canada to meet this demand. Therefore, we are searching for comparable alternatives. One of the imaging devices that was introduced in the clinic is the Radialis PET imager (or RPI). Health Canada, the regulatory body that oversees the use of devices in Canada, has not approved the sale or use of the Radialis PET imager. Health Canada has allowed the Radialis PET imager to be used in this study. We would like to see whether the images obtained for the brain are comparable to those obtained from a PET/CT or PET/MRI scanner. It is a new type of PET imaging device for patients undergoing a PET scan and has been used in Canada for research. RPI is experimental, meaning that this PET scan is not used routinely in patients' care. In comparison to the standard PET devices, RPI is smaller and mobile, meaning it can be moved around easily for use. Also, it can be installed in imaging centers at a lower cost. These advantages make RPI an interesting alternative to the st…

This description comes directly from the study's public registry record.

Talk to the study team

Ur Metser  ·  416-946-4501  ·  ur.metser@uhn.ca

Noosha Yazdani  ·  416-946-4501  ·  noosha.yazdani@uhn.ca

Always discuss trial participation with your own doctor first.

Locations (1)

University Health Network, TorontoToronto, Ontario, CanadaRecruiting

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Source record: clinicaltrials.gov/study/NCT06757569