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Study identifier: NCT06757543 Synced from ClinicalTrials.gov · July 28, 2026
● Recruiting

A Stepped Wedge Cluster Randomised Trial Of Video Versus Direct Laryngoscopy For Intubation Of Newborn Infants

Condition: Intubation · Intubation Complications · Infant, Newborn  ·  Sponsor: University College Dublin

PhaseNA
Planned participants840
Who can joinAll sexes, 0 Minutes to 1 Month
Healthy volunteersNo

About this study

Many newborn babies have difficulty breathing. When babies need a lot of help, a doctor will intubate them - i.e. put a tube into their windpipe (trachea) - so that they can be given support with a breathing machine. Intubation is a difficult procedure, during which many babies have falls in their blood oxygen levels and heart rate. When doctors intubate babies, they use a device called a laryngoscope to identify the entrance to the windpipe. A standard laryngoscope has a light at its tip. When doctors use this device, they insert it into the baby's mouth and then look directly into the mouth to find the entrance (direct laryngoscopy). Less than half of first attempts to insert a tube are successful using this device. More recently, video laryngoscopes have been developed. These devices also have a camera at the tip and display a magnified view of the entrance to the windpipe on a screen. A study at one hospital showed that the doctors there inserted the tube at the first attempt more often when they used a video laryngoscope instead of a standard laryngoscope. This study was not large enough to see whether fewer babies had low oxygen levels or heart rate during the procedure. The goal of this clinical trial is to see whether more newborn babies are intubated at the first attempt without falls in their blood oxygen levels or heart rate when the doctors use video laryngoscopy compared to direct laryngoscopy. Hospitals where doctors routinely intubate babies by looking direct…

This description comes directly from the study's public registry record.

Talk to the study team

Colm P.F. O'Donnell, MB PhD  ·  +35316373100  ·  codonnell@nmh.ie

Janneke Dekker, PhD  ·  +31715266620  ·  j.dekker@lumc.nl

Always discuss trial participation with your own doctor first.

Locations (17)

Clinical Hospital CentreRijeka, CroatiaRecruiting
Clinical Hospital "Holy Spirit"Zagreb, CroatiaRecruiting
University Hospital BrnoBrno, CzechiaRecruiting
General University HospitalPrague, CzechiaRecruiting
Institute for Mother and Child CarePrague, CzechiaRecruiting
Aristotle University of ThessalonikiThessaloniki, GreeceRecruiting
Second Semmelweiss UniversityBudapest, HungaryRecruiting
University of PadovaPadova, ItalyRecruiting
Oslo University HospitalOslo, NorwayRecruiting
Medical University of GdańskGdansk, PolandRecruiting
Medical University of SilesiaKatowice, PolandRecruiting
Provincial Hospital No. 2Rzeszów, PolandRecruiting

+ 5 more locations — full list on the registry record.

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Source record: clinicaltrials.gov/study/NCT06757543