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Study identifier: NCT06756035 Synced from ClinicalTrials.gov · July 29, 2026
● Recruiting

CT-95 in Advanced Cancers Associated With Mesothelin Expression

Condition: Mesothelin-Expressing Tumors · Epithelial Ovarian Cancer · Malignant Pleural Mesothelioma, Advanced  ·  Sponsor: Context Therapeutics Inc.

PhasePhase 1
Planned participants70
Who can joinAll sexes, 18 Years to no upper limit
Healthy volunteersNo

About this study

This is a Phase 1a/1b, first-in-human (FIH), open-label, multi-center dose escalation and expansion study of the safety, pharmacokinetics (PK), pharmacodynamics, and antitumor activity of single-agent CT-95 in subjects with advanced (recurrent, unresectable, or metastatic) cancers associated with MSLN expression.

This description comes directly from the study's public registry record.

Talk to the study team

Context Clinical Development  ·  267-225-7416  ·  cntx-ct95-101@contexttherapeutics.com

Always discuss trial participation with your own doctor first.

Locations (9)

Context Investigational SiteDenver, Colorado, United StatesRecruiting
Context Investigational SiteChicago, Illinois, United StatesRecruiting
Context Investigational SiteGrand Rapids, Michigan, United StatesRecruiting
Context Investigational SiteHackensack, New Jersey, United StatesRecruiting
University of PennsylvaniaPhiladelphia, Pennsylvania, United StatesRecruiting
Context Investigational SitePhiladelphia, Pennsylvania, United StatesRecruiting
Context Investigational SiteNashville, Tennessee, United StatesRecruiting
Context Investigational SiteSan Antonio, Texas, United StatesRecruiting
Context Investigational SiteSan Antonio, Texas, United StatesRecruiting

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Source record: clinicaltrials.gov/study/NCT06756035