Condition: Periodontitis · End-stage Renal Disease · Sponsor: Ain Shams University
Chronic kidney disease (CKD) is a significant public health issue in Egypt, leading to end-stage renal disease (ESRD). ESRD patients often suffer from oral abnormalities due to the disease and medications. Periodontitis is linked to systemic diseases, including renal disease, with inflammation playing a key role. TLR4 genetic variations may influence susceptibility to CKD and periodontitis. This study investigates the association between TLR4 \[Gly/Thr (rs2149356)\] polymorphism and chronic periodontal disease in ESRD patients in Egypt.
This description comes directly from the study's public registry record.
Asmaa Bakr elshaf3y, PHD · 01000093885 · Asmaa.AbdAlRaouf@gu.edu.eg
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| hemodialysis center at Benha University Hospital. | Al Fayyum, Faiyum Governorate, Egypt | Recruiting |
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Source record: clinicaltrials.gov/study/NCT06755372