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Study identifier: NCT06753305 Synced from ClinicalTrials.gov · July 29, 2026
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The Effect of Ozone Therapy on Gingivoplasty

Condition: Gingival Enlargement  ·  Sponsor: Kutahya Health Sciences University

PhaseNA
Planned participants48
Who can joinAll sexes, 18 Years to no upper limit
Healthy volunteersNo

About this study

Ozone therapy after gingivectomy and gingivoplasty has been found to reduce patients' pain levels and positively impact their quality of life. This study aimed to compare the healing potential of the wound surface following gingivectomy and gingivoplasty surgery applied to the maxillary anterior regions with classical periodontal paste application (Coe-pak) using activated oxygen (Cure 09 Active Oxygen) and classical periodontal paste application only (Coe-pak). The study will include 48 systemically healthy patients older than 18 years of age with gingival enlargement in the maxillary anterior region, requiring gingivectomy and gingivoplasty surgery, who applied to Kütahya University of Health Sciences, Faculty of Dentistry, Department of Periodontology and Izmir Democracy University, Faculty of Dentistry, Department of Periodontology. Patients will be evaluated in two different groups as test and control group after surgery. Patients will be randomly divided into study groups by closed envelope method. The test group will receive periodontal paste (Coe-pak) + Ozone therapy (active oxygen (Cure 09 Active Oxygen)) after gingivectomy and gingivoplasty surgery, while the control group will receive only periodontal paste after gingivectomy and gingivoplasty surgery. All patients will undergo gingivectomy and gingivoplasty with the same procedure

This description comes directly from the study's public registry record.

Talk to the study team

Berceste Güler Ayyıldız  ·  +05059359207  ·  berceste.guler@ksbu.edu.tr

Seyma Eken  ·  05518489820  ·  seyma.eken@ksbu.edu.tr

Always discuss trial participation with your own doctor first.

Locations (1)

Kütahya Health Sciences University Faculty of DentistryKütahya, Turkey (Türkiye)Recruiting

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Source record: clinicaltrials.gov/study/NCT06753305