Condition: Stroke · Stroke, Ischemic · Stroke; Sequelae · Sponsor: Hokkaido University Hospital
The goal of this clinical trial is to evaluate if autologous mesenchymal stem cell (HUNS001-01) transplantation therapy can provide neurological recovery in patients with chronic stage of stroke resulting in moderate to severe neurological sequelae. The main questions it aims to answer are: Can HUNS001-01 intracerebral transplantation demonstrate improvement in the mRS of disability for 1 year after intervention? Can HUNS001-01 intracerebral transplantation can be performed without any adverse events for 1 year after intervention? Participants will receive the below interventions. * Screening for the eligibility to enroll the clinical trial (interview, blood test, imaging) * Harvest of platelet concentrates (PC) * Harvest of bone marrows (BM) * Receive intracerebral transplantation surgery of HUNS001-01 * Post-operative rehabilitation * Follow-up studies (until 1 year or termination of the trial)
This description comes directly from the study's public registry record.
Kota Kurisu, M.D., Ph.D. · +81-11-706-1161 · kkurisu0912@gmail.com
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| Hokkaido University Hospital | Sapporo, Hokkaido, Japan | Recruiting |
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Source record: clinicaltrials.gov/study/NCT06752720