Condition: DENV Without Warning Signs · DENV with Warning Signs · Severe Dengue · Sponsor: Karolinska Institutet
The goal of this observational study is to identify biomarkers and host factors associated with dengue severity in patients from dengue-endemic regions. The main question it aims to answer is: Can multi-omics approaches predict disease severity and identify key factors contributing to severe dengue infections? Participants will include individuals with dengue infection, and the study will analyze their blood samples using multi-omics techniques to uncover host immune responses, disease pathogenesis, and cellular pathway interactions. The study will also assess the role of primary and secondary infections, virus serotypes, and immunological factors in disease progression. Findings aim to support disease management, improve severity prediction, and identify potential therapeutic targets to prevent severe outcomes.
This description comes directly from the study's public registry record.
Ujjwal Neogi, PhD · +46 8524 83680 · ujjwal.neogi@ki.se
Always discuss trial participation with your own doctor first.
| Bio Box Guatemala Ong de Investigación, Servicios Y de Medio Ambiente | Guatemala City, Guatemala | Recruiting |
| Manipal Academy of Higher Education (MAHE) | Mangalore, Karnataka, India | Recruiting |
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Source record: clinicaltrials.gov/study/NCT06751836