Condition: Critical Illness · Surgical Procedure, Unspecified · Pulmonary Aspiration · Sponsor: Massachusetts General Hospital
The goal of this clinical trial is to learn if fasting or not fasting before a procedure has an effect on recovery in those who are critically ill. The main questions it aims to answer for patients on a breathing machine who are receiving tube feeding are: * Does the risk of lung complications and death differ between those who are not fasting, which may have a higher chance of allowing tube feeding to enter the lungs, and fasting, which temporarily stops nutrition before a procedure? * Is there a difference in recovery times, hospital stays, infection rates, need for organ support, safety, and nutrition for those who either fast or do not fast before a procedure? * What is the relationship between nutrition and clinical outcomes? Researchers will compare not fasting and fasting to see if it has an effect on recovery. Participants will: * Be assigned by chance (like a coin toss) to one of two groups. One group (fasting group) will have their tube feeding stopped at least 8 hours before their procedure. The other group (not fasting group) will have their tube feeding stopped right before their procedure. * Be monitored via medical record for amount of protein and calories received, and any complications related to fasting/not fasting. * Data from routine electronic medical records will be reviewed to determine how participants are doing 3 months after their procedure. '
This description comes directly from the study's public registry record.
Alexander Nagrebetsky, MD, MSC · 617-724-3292 · anagrebetsky@mgh.harvard.edu
Always discuss trial participation with your own doctor first.
| Stanford Medical Center | Palo Alto, California, United States | Recruiting |
| UCSF Medical Center Parnassus | San Francisco, California, United States | Recruiting |
| University of Colorado Medical Center | Aurora, Colorado, United States | Not Yet Recruiting |
| University of Miami Hospital | Miami, Florida, United States | Not Yet Recruiting |
| McGaw Medical Center of Northwestern | Chicago, Illinois, United States | Recruiting |
| Rush University Medical Center | Chicago, Illinois, United States | Recruiting |
| University of Maryland Medical Center | Baltimore, Maryland, United States | Not Yet Recruiting |
| Mass General Hospital | Boston, Massachusetts, United States | Recruiting |
| Brigham & Women's Hospital | Boston, Massachusetts, United States | Recruiting |
| University of Massachusetts Memorial Medical Center | Worcester, Massachusetts, United States | Recruiting |
| University of Minnesota Medical Center | Minneapolis, Minnesota, United States | Recruiting |
| Columbia University Irvine Medical Center | New York, New York, United States | Recruiting |
+ 7 more locations — full list on the registry record.
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Source record: clinicaltrials.gov/study/NCT06751043