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Study identifier: NCT06747871 Synced from ClinicalTrials.gov · July 28, 2026
● Recruiting

Opioids, Low Nicotine Cigarettes, and Chronic Pain

Condition: Chronic Pain · Tobacco Use · Opioid Substitution Treatment  ·  Sponsor: Duke University

PhaseNA
Planned participants60
Who can joinAll sexes, 21 Years to no upper limit
Healthy volunteersNo

About this study

The purpose of this study is to evaluate the effects of switching to very low nicotine content (VLNC) cigarettes versus normal nicotine content (NNC) cigarettes on craving, withdrawal, and pain among individuals with chronic pain who smoke cigarettes daily and are attending office-based buprenorphine treatment (OBBT).

This description comes directly from the study's public registry record.

Talk to the study team

Clinical Research Coordinator  ·  919-907-9955  ·  ta141@duke.edu

Clinical Research Coordinator  ·  984-327-6157  ·  lgf12@duke.edu

Always discuss trial participation with your own doctor first.

Locations (1)

North PavilionDurham, North Carolina, United StatesRecruiting

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Source record: clinicaltrials.gov/study/NCT06747871