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Study identifier: NCT06747585 Synced from ClinicalTrials.gov · July 29, 2026
● Recruiting

A Study to Investigate ALE.P02 as Monotherapy in Adult Patients With Selected CLDN1+ Solid Tumors

Condition: Squamous Non-small-cell Lung Cancer · Head and Neck Squamous Cell Carcinoma · Cervical Squamous Cell Carcinoma  ·  Sponsor: Alentis Therapeutics AG

PhasePhase 1/Phase 2
Planned participants170
Who can joinAll sexes, 18 Years to no upper limit
Healthy volunteersNo

About this study

The purpose of this study is to evaluate the safety, tolerability, pharmacokinetic, pharmacodynamic, preliminary anti-tumor activity, and to determine the recommended Phase II dose (RP2D) of the ALE.P02 monotherapy in adult patients with selected squamous solid tumors.

This description comes directly from the study's public registry record.

Talk to the study team

Alentis Clinical Trial Contact  ·  +41782304288  ·  patientinfo@alentis.ch

Always discuss trial participation with your own doctor first.

Locations (41)

Mayo Foundation for Medical Education and Research - Mayo ClScottsdale, Arizona, United StatesRecruiting
Providence Medical FoundationFullerton, California, United StatesRecruiting
USC Norris Comprehensive Cancer CenterLos Angeles, California, United StatesRecruiting
Yale Comprehensive Cancer CenterNew Haven, Connecticut, United StatesRecruiting
The University of Chicago Medical Center - OncologyChicago, Illinois, United StatesRecruiting
Norton Cancer Institue DowntownLouisville, Kentucky, United StatesRecruiting
Hackensack University Medical CenterHackensack, New Jersey, United StatesRecruiting
NEXT Oncology VirginiaFairfax, Virginia, United StatesRecruiting
Institut BergonieBordeaux, FranceRecruiting
Centre Georges Francois Leclerc - Oncologie MedicaleDijon, FranceRecruiting
CHRU De Lille- Hôpital Claude Huriez - Medical OncologyLille, FranceRecruiting
AP-HM Hôpital de La Timone CEPCMMarseille, FranceRecruiting

+ 29 more locations — full list on the registry record.

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Source record: clinicaltrials.gov/study/NCT06747585