● Recruiting

A Study to Investigate the Efficacy and Safety of Sonrotoclax Plus Zanubrutinib Compared With Placebo Plus Zanubrutinib in Adults With Relapsed/Refractory Mantle Cell Lymphoma (CELESTIAL-RRMCL)

Condition: Mantle Cell Lymphoma · B Cell Lymphoma · Sponsor: BeOne Medicines

PhasePhase 3

Planned participants300

Who can joinAll sexes, 18 Years to no upper limit

Healthy volunteersNo

About this study

The goal of this study is to compare how well sonrotoclax plus zanubrutinib works versus zanubrutinib plus placebo in treating adults with relapsed/refractory (R/R) mantle cell lymphoma (MCL). This study will also look at the safety of sonrotoclax plus zanubrutinib versus zanubrutinib plus placebo.

This description comes directly from the study's public registry record.

Talk to the study team

Study Director · 1.877.828.5568 · clinicaltrials@beonemed.com

Always discuss trial participation with your own doctor first.

Locations (155)

University of Alabama At Birmingham Hospital	Birmingham, Alabama, United States	Recruiting
University of Arizona Cancer Center	Tucson, Arizona, United States	Recruiting
Ucsf Fresno	Fresno, California, United States	Recruiting
Kaiser Permanente Southern California	Irvine, California, United States	Recruiting
Yale University Yale Cancer Center	New Haven, Connecticut, United States	Recruiting
Memorial Cancer Institute, Memorial Healthcare System	Pembroke Pines, Florida, United States	Recruiting
Cleveland Clinic Florida	Weston, Florida, United States	Recruiting
Rush University Medical Center	Chicago, Illinois, United States	Recruiting
University of Chicago Medical Center	Chicago, Illinois, United States	Recruiting
Fort Wayne Medical Oncology and Hematology	Fort Wayne, Indiana, United States	Recruiting
Mission Cancer and Blood	Waukee, Iowa, United States	Recruiting
Our Lady of the Lake Hospital	Baton Rouge, Louisiana, United States	Recruiting

+ 143 more locations — full list on the registry record.

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Source record: clinicaltrials.gov/study/NCT06742996