Condition: Acute T Lymphpblastic Leukemia/Lymphoma · Sponsor: First Affiliated Hospital of Zhejiang University
Acute T cell lymphoblastic leukemia/lymphoma (T-ALL/LBL) is an aggressive type of leukemia that results from the malignant evolution of T-lineage progenitor cells at different differentiation stages. After induction chemotherapy and consolidation chemotherapy, there are still about 30% of patients who cannot achieve complete remission of clinical symptoms or negative MRD. This is also an important factor for the recurrence of ALL patients. In addition, most relapsed T-ALL/LBL patients relapse during first-line treatment. Once the disease relapses, it is difficult to cure for most young and adult patients, and the overall survival rate of patients is less than 10%.
This description comes directly from the study's public registry record.
Jie Jin, M.D. · +8657187236896 · jiej0503@163.com
Chenying Li, Ph.D. · +8657187236896 · lcy890823@126.com
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| The First Affiliated Hospital, Zhejiang University School of Medicine | Hangzhou, Zhejiang, China | Recruiting |
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Source record: clinicaltrials.gov/study/NCT06742463