Condition: Acute Ischemic Stroke · Transient Ischemic Attack · Sponsor: Universitätsklinikum Hamburg-Eppendorf
The goal of this observational study is to * to investigate the prevalence and time course of autonomic dysfunction in acute ischemic stroke patients; * to evaluate the influence of lesion location on autonomic dysfunction; * to identify patterns of structural and functional brain connectivity within the central autonomic control circuits associated with autonomic dysfunction; and * to explore causal models of the link between brain lesions; cardiac, immunological and endocrine biomarkers; and dysautonomia. Researchers will compare patients with acute ischemic stroke to patients with transient ischemic attacks to study the effect of acute ischemic brain lesions. Participants will * undergo cardiovascular autonomic function testing; * receive structural and functional MR imaging; * provide blood samples for determinaton of serological biomarkers auf dysautonomia.
This description comes directly from the study's public registry record.
Eckhard Schlemm · +49 152 228 98447 · e.schlemm@uke.de
Thies Ingwersen · +49 152 228 34568 · thi.ingwersen@uke.de
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| University Medical Center Hamburg-Eppendorf | Hamburg, Free and Hanseatic City of Hamburg, Germany | Recruiting |
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Source record: clinicaltrials.gov/study/NCT06740942