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Study identifier: NCT06740266 Synced from ClinicalTrials.gov · July 28, 2026
● Recruiting

The Impact of an Evidence-Based Parenting Service on Maternal Sensitivity and Infant Cellular Aging in a Population of Under-Resourced Families

Condition: Parent Child Relationship · Child Social-Emotional Development · Telomere Length  ·  Sponsor: University of Washington

PhaseNA
Planned participants250
Who can joinFemale, 18 Years to no upper limit
Healthy volunteersYes

About this study

The goal of this clinical trial study is to learn how stress in childhood, or Early Life Adversity (ELA), gets "under the skin" and influences long-term health. The investigators will test if the support given to parents of young children reduces childhood stress. The investigators will also test if the effects of mother's stress and Early Life Adversity can be passed down to children. Can it impact the child's long-term health? Researchers will compare the Promoting First Relationships® in Primary Care (PFR in PC) parenting program with Usual Care to see if PFR reduces mothers' stress, improves mother's sensitivity, and reduces accelerated cellular aging. Participants will: * Be randomized to receive PFR in PC or Usual Care. PFR in PC is an evidence-based 10-week home visiting service, with 2 extra sessions at the WakeMed pediatric clinic. Usual Care is the health care and general services offered to families at the WakeMed pediatric clinic. * Have in-home research visits at the start of the study (Time 1, T1), about 6 months later (Time 2, T2), and 12 months later (Time 3, T3). Information collected at these visits includes: * Answering questions about your background, past and current stress, physical and mental health, parenting behaviors, and child behavior problems (T1, T2, T3). * Being videotaped doing a short teaching activity. * Having a small amount of blood collected from the mother by finger prick (T1, T3). * Having a small amount of blood collected fro…

This description comes directly from the study's public registry record.

Talk to the study team

Monica Oxford, PhD  ·  206-685-6107  ·  mloxford@uw.edu

Mary Jane Lohr, MS  ·  1-206-616-3373  ·  mjlohr@uw.edu

Always discuss trial participation with your own doctor first.

Locations (1)

WakeMed Health & HospitalsRaleigh, North Carolina, United StatesRecruiting

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Source record: clinicaltrials.gov/study/NCT06740266