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Study identifier: NCT06734598 Synced from ClinicalTrials.gov · July 29, 2026
● Recruiting

Efficacy of Botox Injection of the Masticatory Muscles in Head &Neck Cancer Patients with Trismus After Radiotherapy

Condition: Trismus · Head and Neck Cancer · Radiation Therapy Recipient  ·  Sponsor: National Taiwan University Hospital

PhasePhase 4
Planned participants120
Who can joinAll sexes, 18 Years to no upper limit
Healthy volunteersNo

About this study

Trismus is a common side effect in head and neck cancer patients after radiation therapy. This project aims to explore the therapeutic effect of Botulinum toxin (Botox) injection to the masticatory muscles in the above-mentioned patients. In this project, Botulinum toxin will be injected into the masticatory muscles (medial pterygoid and masticatory muscles), combined with oral rehabilitation exercises, to reduce the patient's masticatory muscle tension and spasm. Patient's mouth opening range, quality of life, trismus condition and pain will be evaluated to understand its efficacy.

This description comes directly from the study's public registry record.

Talk to the study team

Dr. Chen  ·  +88623123456  ·  b00401020@ntu.edu.tw

Always discuss trial participation with your own doctor first.

Locations (1)

National Taiwan University HospitalTaipei, TaiwanRecruiting

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Source record: clinicaltrials.gov/study/NCT06734598