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Study identifier: NCT06734351 Synced from ClinicalTrials.gov · July 29, 2026
● Recruiting

A Study to Evaluate Safety and Effectiveness of NOA VOLUME Injectable Gel in Adult Participants Compared to JUVÉDERM VOLUMA XC for Improvement of Mid-Face Volume

Condition: Mid Face Volume Deficit  ·  Sponsor: AbbVie

PhasePhase 3
Planned participants231
Who can joinAll sexes, 22 Years to no upper limit
Healthy volunteersNo

About this study

Facial fullness is often regarded as a characteristic feature of a youthful face. Chronic reduction of collagen, elastin, and glycosaminoglycans contribute to the facial volume loss that characterizes the aging face. Volume restoration by replacing or augmenting soft tissue is critical to successful facial rejuvenation. NOA VOLUME is a crosslinked Hyaluronic Acid (HA) injectable gel formulated with lidocaine that was developed to provide a safe, minimally invasive method of improving mid-face volume deficit. The purpose of this study is to assess safety and effectiveness of NOA VOLUME in adult participants seeking improvement of mid-face volume compared to JUVÉDERM VOLUMA XC (VOLUMA XC). NOA VOLUME is an investigational device being developed for the improvement of mid-face volume. There will be 2 cohorts in this study. Participants will receive either NOA VOLUME or VOLUMA XC. Around 231 adult participants seeking improvement of mid-face volume will be enrolled in the study at approximately 15 sites in the United States. Participants will receive either NOA VOLUME or VOLUMA XC injections in the cheek area on Day 1. Participants will receive optional touch-up treatment at Day 31 and optional repeat treatment at Month 18 and will be followed up for up to 31 months.

This description comes directly from the study's public registry record.

Talk to the study team

ABBVIE CALL CENTER  ·  844-663-3742  ·  abbvieclinicaltrials@abbvie.com

Always discuss trial participation with your own doctor first.

Locations (15)

Total Skin and Beauty Dermatology Center /ID# 258164Birmingham, Alabama, United StatesRecruiting
Advanced Research Associates - Glendale /ID# 276812Glendale, Arizona, United StatesRecruiting
West Dermatology La Jolla /ID# 278590San Diego, California, United StatesRecruiting
Susan H. Weinkle MD /ID# 258160Bradenton, Florida, United StatesRecruiting
Hevia Cosmetic Dermatology /ID# 258165Coral Gables, Florida, United StatesRecruiting
Skin Research Institute LLC /ID# 258158Coral Gables, Florida, United StatesRecruiting
Atlanta Biomedical Clinical Research /ID# 261210Atlanta, Georgia, United StatesRecruiting
Pure Dermatology /ID# 258168Metairie, Louisiana, United StatesRecruiting
Aesthetic Center at Woodholme /ID# 258166Baltimore, Maryland, United StatesRecruiting
Edwin F. Williams III, MD FACS of LATHAM P.C. D/B/A THE REJUVA CENTER /ID# 261211Latham, New York, United StatesRecruiting
Jane Yoo MD /ID# 279811New York, New York, United StatesRecruiting
Northwest Dermatology Institute /ID# 258167Portland, Oregon, United StatesRecruiting

+ 3 more locations — full list on the registry record.

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Source record: clinicaltrials.gov/study/NCT06734351