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Study identifier: NCT06733974 Synced from ClinicalTrials.gov · July 28, 2026
● Recruiting

A Multifaceted Intervention Strategy for Relatives of End-of-life Patients in the Emergency Department

Condition: Grief Disorder, Prolonged  ·  Sponsor: Assistance Publique - Hôpitaux de Paris

PhaseNA
Planned participants924
Who can joinAll sexes, 18 Years to no upper limit
Healthy volunteersYes

About this study

In France, a study has reported that about 0.2% of patients visiting the ED died in the ED. A large survey of 145 EDs in 3 French speaking countries has reported that a median of 2 patients dies each week in each ED and its observation unit. After the death of a loved one, prolonged grief disorder (PGD) is a bereavement-specific syndrome that is defined as intense, prolonged yearning and preoccupation with thoughts of the deceased. PGD prevalence after the loss of a relative was 10% (95%CI 7-14) in the general population.Post-traumatic stress disorder (PTSD) is a mental health condition that is triggered by experiencing a terrifying event. Symptoms may include flashbacks, nightmares, and severe anxiety. The reported lifetime PTSD prevalence is 7% among adults in the general population. Admission and death in the hospital can be a traumatic and stressful experience for relatives, and is associated with an up to 50% risk of PGD and PTSD at 6 months. In the setting of ICU, several studies have reported that implementation of simple human interventions (information supports including written information on end-of-life care and pro-active communication strategy with systematic interviews with relatives), was associated with a lower risk of PTSD at 3 months (45% vs. 69%) and PGD at 6 months (21% vs 57%). Furthermore, it has been reported that offering the possibility of relatives to be present during nursing and medical care may be beneficial. In the out of hospital setting, off…

This description comes directly from the study's public registry record.

Talk to the study team

Yonathan FREUND, PU-PH  ·  +33663549017  ·  yonathan.freund@aphp.fr

Mélanie ROUSSEL, MD-PhD  ·  melanie.roussel@chu-rouen.fr

Always discuss trial participation with your own doctor first.

Locations (1)

Emergency Department Hospital Pitié-SalpêtrièreParis, Paris, FranceRecruiting

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Source record: clinicaltrials.gov/study/NCT06733974