Condition: Nasopharyngeal Carcinoma · Sponsor: National University Hospital, Singapore
Primary objective: Evaluate and compare incidence of acute and long-term taste dysfunction in chemoradiation plus dental stent group vs. chemoradiation group, using objective-measured taste strip test, and patient-reported taste ability and toxicity. Secondary objectives: 1. Evaluate and compare incidence of acute and long-term toxicities (excluding taste) and patient-reported quality of life between chemoradiation plus dental stent group and chemoradiation group. 2. Evaluate and compare tumor response, overall survival, and failure-free survival between chemoradiation plus dental stent group and chemoradiation group. 3. Analyze dosimetric parameters of taste bud bearing tongue mucosa, ipsilateral/ contralateral parotid and submandibular glands extracted from RT plans and correlate with taste impair
This description comes directly from the study's public registry record.
Shing Fung Lee, MBBS · +6567726392 · leesf@nuhs.edu.sg
Fatin Aliyah Binte Hussin, BSc · +6567723079 · fatin_hussin@nuhs.edu.sg
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| Singapore Institute of Food and Biotechnology Innovation | Singapore, Singapore | Not Yet Recruiting |
| National University Hospital | Singapore, Singapore | Recruiting |
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Source record: clinicaltrials.gov/study/NCT06733948