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Study identifier: NCT06733714 Synced from ClinicalTrials.gov · July 28, 2026
● Recruiting

Association of Transcranial Alternating Current Stimulation with Digital Cognitive Training for Cognitive Remediation in Older Adults

Condition: Cognitive Dysfunction · Alzheimer Disease · Mild Cognitive Impairment  ·  Sponsor: Universidade Federal do Rio de Janeiro

PhaseNA
Planned participants40
Who can joinAll sexes, 50 Years to no upper limit
Healthy volunteersYes

About this study

BACKGROUND Cognitive decline in older adults, especially those who develop Mild Cognitive Impairment and Alzheimer's Disease, currently has limited options of pharmacological treatments, with modest efficacy. Digital Cognitive Training (DCT) and Transcranial Alternating Current Stimulation (tACS) are two promising tools for cognitive remediation in this population. In this exploratory study, we investigate feasibility, tolerability and preliminary effects of the association of both interventions in older adults with cognitive complaints. METHODS Older adults with cognitive complaints are being enrolled for this study, which comprises 5 daily sessions of 30 minutes of DCT using the BrainHQ platform while simultaneously receiving theta tACS (6Hz, 1.6mA) targeting the Left Dorsolateral Prefrontal Cortex.

This description comes directly from the study's public registry record.

Talk to the study team

Rogerio Panizzutti, Professor  ·  +55:21-3938-5588  ·  rogerio.panizzutti@ipub.ufrj.br

Brunno Costa, PhD student  ·  +55 31996773008  ·  fc_brunno@hotmail.com

Always discuss trial participation with your own doctor first.

Locations (1)

Clínica da Memória - IPUB / UFRJRio de Janeiro, Rio de Janeiro, BrazilRecruiting

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Source record: clinicaltrials.gov/study/NCT06733714