Condition: Strabismus · Sponsor: Fondazione Policlinico Universitario Agostino Gemelli IRCCS
Strabismus is a clinical condition characterized by the failure of the visual axes of the two eyes to align on the stared object. There are many possible causes of strabismus, but it can be divided into two main groups: concomitant strabismus, which is characterized by an almost equal angle of deviation in all positions of gaze, and incomitant or paralytic strabismus, which is characterized by a deficit of ocular motility in one or more directions of gaze. Depending on the age of onset, congenital strabismus and acquired strabismus are distinguished. Concomitant strabismus and incomitant strabismus can occur in both plastic age and adults. They are accompanied by diplopia or confusion if they arise in adulthood; there is no diplopia if they arise in plastic age due to cortical compensation mechanisms such as suppression or abnormal retinal matching. Causes of incomitant strabismus in adults can be: decompensation of a preexisting heterophoria; acute incomitant strabismus; injury to fusional centers. Paralytic incomitant strabismus is characterized by a reduction in the force developed by one or more muscles of an eye. Among incomitant strabismus, restrictive strabismus represent clinical pictures of very different etiology united by a single distinguishing feature: the existence of a mechanical obstacle to the free movement of the bulb in the orbit that prevents or reduces the excursion of the eye in one or more directions of gaze. In about 4% of the young population, the se…
This description comes directly from the study's public registry record.
Annabella Salerni, MD · +390630154382 · annabella.salerni@policlinicogemelli.it
Letizia Castelli, PhD · +390630154382 · letizia.castelli@unicatt.it
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| Fondazione Policlinico Universitario A. Gemelli IRCCS | Roma, RM, Italy | Recruiting |
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Source record: clinicaltrials.gov/study/NCT06733220