Condition: Acute Respiratory Syndrome Distress · Positive End-Expiratory Pressure · Mechanical Ventilation · Sponsor: Vietnam Military Medical University
Acute respiratory distress syndrome (ARDS) in its moderate to severe forms is associated with high mortality. Mechanical ventilation (MV) remains the cornerstone of ARDS management but carries a significant risk of ventilator-induced lung injury (VILI). Positive end-expiratory pressure (PEEP), a fundamental component of MV, is widely utilized in clinical practice; however, optimal PEEP selection for patients with moderate to severe ARDS remains a complex and unresolved challenge. Electrical impedance tomography (EIT), a bedside imaging modality that evaluates regional ventilation distribution, offers a means of individualizing PEEP settings in mechanically ventilated patients. By balancing the competing risks of alveolar overdistension and collapse, EIT facilitates precision in PEEP titration. This study compares the impact of EIT-guided PEEP selection versus the conventional low FiO2-PEEP table on blood oxygenation and pulmonary mechanics.
This description comes directly from the study's public registry record.
Trung Van Dinh, MD · (+84) 988519190 · dinhvantrung.ptgh@gmail.com
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| Intensive Care Center, Bach Mai Hospital | Hanoi, Vietnam | Recruiting |
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Source record: clinicaltrials.gov/study/NCT06733168