Condition: Rapid Sequence Induction · Sponsor: Nantes University Hospital
The best hypnotic choice to optimize the balance between good intubation condition quality and hemodynamic stability during RSI performed in the operating theatre remained to be investigated. Therefore, a randomized study evaluating the efficacy of propofol, ketamine, and a combination of both is appropriate. So, we designed the HyPnotiKs randomized controlled study to investigate the efficacy of these hypnotic drugs in patients undergoing RSI in the operating theatre. The primary endpoint will be the successful tracheal intubation at the first attempt without major arterial hypotension event.
This description comes directly from the study's public registry record.
Nicolas GRILLOT, MD · 02 53 48 22 24 · nicolas.grillot@chu-nantes.fr
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| Chr Angers | Angers, France | Recruiting |
| CHRU de Brest Hôpital Cavale Blanche | Brest, France | Recruiting |
| Ch Louis Pasteur | Chartres, France | Not Yet Recruiting |
| CHU Dijon | Dijon, France | Recruiting |
| CHU Grenoble Alpes | Grenoble, France | Not Yet Recruiting |
| CHD Vendée | La Roche-sur-Yon, France | Recruiting |
| APHP Bicêtre | Le Kremlin-Bicêtre, France | Not Yet Recruiting |
| CH Le Mans | Le Mans, France | Recruiting |
| CHU Lille Hopital Salengro | Lille, France | Recruiting |
| CHU Lille Hôpital Claude Huriez | Lille, France | Recruiting |
| CHU Lyon Hôpital Sud | Lyon, France | Not Yet Recruiting |
| HCL Lyon Croix-Rousse | Lyon, France | Not Yet Recruiting |
+ 8 more locations — full list on the registry record.
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Source record: clinicaltrials.gov/study/NCT06733129