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Study identifier: NCT06732414 Synced from ClinicalTrials.gov · July 28, 2026
● Recruiting

A Biorepository of Multiple Allergic Diseases (MADREP) With Longitudinal Follow-Up

Condition: Allergy, Sinus Disorders, Atopic Diseases, Asthma, Allergic Rhinitis, Atopic Dermatitis, EoE, Drug a  ·  Sponsor: National Institute of Allergy and Infectious Diseases (NIAID)

PhaseN/A
Planned participants10000
Who can joinAll sexes, 3 Years to 100 Years
Healthy volunteersNo

About this study

Background: Allergic or sinus diseases can affect the skin, sinuses, airways, and other parts of the body. Examples include pollen and environmental allergies, food allergies, asthma, and eczema. To learn more about how to prevent and treat these diseases, researchers need to study data, blood, fluid, and tissue samples from people affected by them. Objective: To collect data, blood, fluid, and tissue samples from people with allergic or sinus diseases. Eligibility: People aged 3 to 100 years with allergic or sinus diseases. Design: Participants will have at least one clinic visit, and most participants will have a baseline visit, annual visit, and an end of study visit. The duration of the study is 1 to 3 years. During the first clinic visit, the following procedures will be done to collect data, blood, fluid, and tissue samples: * Blood will be collected. * Cells and fluid may be collected from the inside of the nose using a long swab, and a small piece of skin may be scraped from inside the nose. * Skin cells will be collected by rubbing with a cotton swab. * A urine sample will be collected. * Allergy skin prick tests. Allergy-causing substances will be placed on the back or arm and the skin underneath gently scratched. If the participant is allergic to the substance, the skin may become red, itchy, and swollen locally ( at the site of the test). * Lung function test. Participants will breathe into a machine that measures the air moving in and out of their lungs. …

This description comes directly from the study's public registry record.

Talk to the study team

Hye Jeong C Bolan, R.N.  ·  (301) 594-1233  ·  NIAIDMADREP@NIH.GOV

Paneez Khoury, M.D.  ·  (301) 402-3673  ·  paneez.khoury@nih.gov

Always discuss trial participation with your own doctor first.

Locations (1)

National Institutes of Health Clinical CenterBethesda, Maryland, United StatesRecruiting

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Source record: clinicaltrials.gov/study/NCT06732414