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Study identifier: NCT06727487 Synced from ClinicalTrials.gov · July 29, 2026
● Recruiting

OvS Breast: Ovarian Suppression in Breast Cancer Interventions

Condition: Breast Neoplasms  ·  Sponsor: Universidad Pontificia Comillas

PhaseNA
Planned participants30
Who can joinFemale, 18 Years to 45 Years
Healthy volunteersNo

About this study

The goal of this clinical trial is to compare a combined intervention based on physical exercise, nutritional control, and individualized psycho-oncological support can achieve weight control and maintain adequate body composition in premenopausal women with localized BC with ER and/or PR expression who receive aLHRH in combination with TAM or AI as part of adjuvant treatment. The study's primary objectives are to evaluate the impact of the combined intervention on weight reduction and favorable modification of body composition in terms of reduction in body fat and increase in lean mass. The secondary objectives aim to evaluate the impact of the combined intervention program on CRF, heart rate (HR), capillary lactate levels, upper and lower body strength, physical functionality, and patient-reported outcomes (PROs). (exercise level, asthenia, self-perception, anxiety and depression), blood count and biochemistry values that could be modified, nutritional situation, and side effects of treatments.

This description comes directly from the study's public registry record.

Talk to the study team

Julio C de la Torre-Montero, Ph.D  ·  +34678581021  ·  juliodelatorre@comillas.edu

Maria Jesús Martínez Beltrán, Ph.D  ·  mjesus.martinez@comillas.edu

Always discuss trial participation with your own doctor first.

Locations (2)

Universidad Pontificia ComillasMadrid, SpainRecruiting
Hospital General Universitario Gregorio MarañónMadrid, SpainRecruiting

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Source record: clinicaltrials.gov/study/NCT06727487