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Study identifier: NCT06726421 Synced from ClinicalTrials.gov · July 29, 2026
● Recruiting

Systemic Therapy Alone or With Stereotactic Body Radiotherapy for Oligometastatic Kidney Cancer (STROKER Study)

Condition: Renal Cell Carcinoma (Kidney Cancer) · Kidney Cancer Metastatic · Renal Cell Carcinoma Metastatic  ·  Sponsor: Sun Yat-sen University

PhasePhase 3
Planned participants252
Who can joinAll sexes, 18 Years to no upper limit
Healthy volunteersNo

About this study

This phase III randomized controlled trial evaluates the efficacy of stereotactic body radiation therapy (SBRT) in oligometastatic renal cell carcinoma. The study aims to determine if the addition of SBRT to standard systemic therapy prolong survival compared to the standard systemic therapy alone. In addition, the study will explore the impact of this combined modality therapy on patients' toxicity and quality of life. The researchers will compare SBRT plus standard systemic therapy to standard systemic therapy alone, which is targeted agents and immunotherapy in this case, to determine if SBRT could prolong survival.

This description comes directly from the study's public registry record.

Talk to the study team

Liru He, PhD  ·  0086-13631365597  ·  helir@wy.sysucc.org.cn

Fangjian Zhou, PhD  ·  0086-13922735659  ·  zhoufj@wy.sysucc.org.cn

Always discuss trial participation with your own doctor first.

Locations (9)

Union Hospital, Fujian Medical UniversityFuzhou, Fujian, ChinaRecruiting
Sun Yat-sen University Cancer CenterGuangzhou, Guangdong, ChinaRecruiting
Union Hospital, Tongji Medical College, Huazhong University of Science and TechnologyWuhan, Hubei, ChinaRecruiting
The First Hospital of Jilin UniversityChangchun, Jilin, ChinaRecruiting
West China Hospital, Sichuan UniversityChengdu, Sichuan, ChinaRecruiting
The First Affiliated Hospital of Wenzhou Medical UniversityWenzhou, Zhejiang, ChinaRecruiting
Cancer Hospital, Chinese Academy of Medical SciencesBeijing, ChinaNot Yet Recruiting
Peking University First HospitalBeijing, ChinaRecruiting
Fudan University Shanghai Cancer CenterShanghai, ChinaRecruiting

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Source record: clinicaltrials.gov/study/NCT06726421