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Study identifier: NCT06726291 Synced from ClinicalTrials.gov · July 29, 2026
● Recruiting

Akynzeo as Antiemetic Treatment in Patients With Endometrial Cancer

Condition: Endometrial Cancer  ·  Sponsor: Fondazione IRCCS Istituto Nazionale dei Tumori, Milano

PhasePhase 4
Planned participants84
Who can joinFemale, 18 Years to no upper limit
Healthy volunteersNo

About this study

The clinical trial concerns the use of an innovative \"anti-emetic\" drug (that is, anti-vomiting and nausea) in subjects affected by endometrial cancer. It is addressed to patients who have never received chemotherapy before and are about to start a treatment with platinum and taxanes with or without immunotherapy for endometrial cancer. The primary objective of the study is to learn if the drug is able to avoid the occurrence of vomiting and post- nausea chemotherapy within 120 hours after cycle 1 with carboplatin and paclitaxel with or without immunotherapy. Partecipants will take the drug before the chemotherapy/immunotherapy (single dose at day one of each cycle of therapy, that is one capsule before treatment). The entire duration of participation in the study may extend to the fourth cycle of chemotherapy/immunotherapy. Patients will fill in questionnaires and keep a diary of the number and intensity of symptoms (vomiting and nausea).

This description comes directly from the study's public registry record.

Talk to the study team

Monika Ducceschi, MD  ·  +39 02 2390 2342  ·  monika.ducceschi@istitutotumori.mi.it

Mara Mantiero, MD  ·  +39 02 2390 2342  ·  mara.mantiero@istitutotumori.mi.it

Always discuss trial participation with your own doctor first.

Locations (8)

ASST Spedali Civili di BresciaBrescia, BS, ItalyNot Yet Recruiting
ASST Lecco - A. Manzoni HospitalLecco, LC, ItalyRecruiting
Istituto Oncologico VenetoPadova, PD, ItalyRecruiting
Centro di Riferimento Oncologico (CRO) IRCCSAviano, PN, ItalyNot Yet Recruiting
Azienda Ospedaliera Ordine Mauriziano di TorinoTorino, TO, ItalyActive Not Recruiting
AOU Città della Salute e della Scienza di TorinoTorino, TO, ItalyNot Yet Recruiting
Fondazione IRCCS Istituto Nazionale dei TumoriMilan, ItalyRecruiting
Istituto Europeo di OncologiaMilan, ItalyActive Not Recruiting

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Source record: clinicaltrials.gov/study/NCT06726291