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Study identifier: NCT06724237 Synced from ClinicalTrials.gov · July 29, 2026
● Recruiting

Testing Whether High Dose Chemotherapy and Infusion of the Patients' Own Stem Cells Improves Survival in Patients With Peripheral T-cell Lymphoma Who Achieved a Complete Response at the End of the Initial Chemotherapy

Condition: Anaplastic Large Cell Lymphoma, ALK-Negative · Follicular Helper T-Cell Lymphoma · Follicular Helper T-Cell Lymphoma, Angioimmunoblastic-Type  ·  Sponsor: Eastern Cooperative Oncology Group

PhasePhase 3
Planned participants294
Who can joinAll sexes, 18 Years to 75 Years
Healthy volunteersNo

About this study

This phase III trial compares the effect of high dose chemotherapy and the patients' own (autologous) stem cells to observation only in patients with peripheral T-cell lymphoma who achieved a complete response after initial chemotherapy. Usual treatment after a complete response may include observation or high dose chemotherapy followed by an autologous stem cell transplant, however, it is not known if a transplant if beneficial. Giving chemotherapy before a stem cell transplant helps kill cancer cells in the body and helps make room in the patient's bone marrow for new blood-forming cells (stem cells) to grow. Stem cells removed prior to treatment are then returned to the patient to replace the blood forming cells that were destroyed by the chemotherapy. Giving high dose chemotherapy followed by an autologous stem cell transplant may be more effective compared to observation only in treating patients with peripheral T-cell lymphoma who have achieved a complete response after initial chemotherapy.

This description comes directly from the study's public registry record.

Talk to the study team

Pamela Cogliano  ·  857-504-2900  ·  ecog.rss@jimmy.harvard.edu

Always discuss trial participation with your own doctor first.

Locations (158)

University of Alabama at Birmingham Cancer CenterBirmingham, Alabama, United StatesNot Yet Recruiting
Anchorage Associates in Radiation MedicineAnchorage, Alaska, United StatesRecruiting
Alaska Breast Care and Surgery LLCAnchorage, Alaska, United StatesRecruiting
Alaska Oncology and Hematology LLCAnchorage, Alaska, United StatesRecruiting
Alaska Women's Cancer CareAnchorage, Alaska, United StatesRecruiting
Katmai Oncology GroupAnchorage, Alaska, United StatesRecruiting
Providence Alaska Medical CenterAnchorage, Alaska, United StatesRecruiting
Fairbanks Memorial HospitalFairbanks, Alaska, United StatesActive Not Recruiting
Mayo Clinic Hospital in ArizonaPhoenix, Arizona, United StatesRecruiting
Banner University Medical Center - TucsonTucson, Arizona, United StatesRecruiting
University of Arizona Cancer Center-North CampusTucson, Arizona, United StatesRecruiting
Providence Saint Joseph Medical Center/Disney Family Cancer CenterBurbank, California, United StatesRecruiting

+ 146 more locations — full list on the registry record.

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Source record: clinicaltrials.gov/study/NCT06724237