Condition: Type 2 Diabetes Mellitus · Prediabetes (Insulin Resistance, Impaired Glucose Tolerance) · Prediabetic State · Sponsor: Instituto de Ciencia y Tecnología de Alimentos y Nutrición
This clinical trial aims at assessing whether consumption of olive pomace oil in the diet may benefit persons with type 2 diabetes mellitus or persons at risk of developing the disease (prediabetic persons). The main questions the study aims to answer are: * May olive pomace oil prevent a high increase of blood glucose levels when consumed in a meal together with carbohydrates in diabetic/prediabetic patients? * May olive pomace oil decrease fasting blood glucose levels of diabetic/prediabetic patients after consuming it daily? * May daily consumption of olive pomace oil improve glucose homeostasis and other alterations like elevated blood lipids or inflammation, which also affect persons with diabetes or prediabetes? Researchers will compare the effect of consuming olive pomace oil to the effects of a comparison oil (high-oleic acid sunflower oil). Participants will: In different days, they will consume white bread alone or the oils (olive pomace oil, high-oleic acid sunflower oil or extra virgin olive oil) spread on white bread and blood will be collected at different times during 2 h. This study to observe the increase of blood glucose after a carbohydrate-rich breakfast will be part of the so-called "postprandial" study, and will be conducted during 3 weeks, during which participants will consume corn oil on a daily basis. Participants will also take part in the "chronic" study, that will last 22 weeks in total. During this study, they will firstly "wash" the effect…
This description comes directly from the study's public registry record.
Laura Bravo, Professor · +34 91 5492300 · lbravo@ictan.csic.es
Beatriz Sarria, Dr · +34 91 5492300 · beasarria@ictan.csic.es
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| Institute of Food Science, Technology and Nutrition (ICTAN-CSIC) | Madrid, Madrid, Spain | Recruiting |
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Source record: clinicaltrials.gov/study/NCT06723886