Condition: Recurrent B-Cell Non-Hodgkin Lymphoma · Recurrent Polymorphic Post-Transplant Lymphoproliferative Disorder · Refractory B-Cell Non-Hodgkin Lymphoma · Sponsor: Reem Karmali
This phase II trial tests how well the combination of epcoritamab and lenalidomide work in treating patients with immunodeficiency-related large B-cell lymphoma that does not respond to treatment (refractory) or that has come back after a period of improvement (relapsed). Epcoritamab is an immunotherapy that engages T-cells in the immune system to help redirect their killing effects against lymphoma cells. Lenalidomide can modulate the immune system to enhance killing effects of lymphoma by the immune system as well. Giving patients a combination of epcoritamab and lenalidomide may work better in treating refractory or relapsed immunodeficiency-related large B-cell lymphoma.
This description comes directly from the study's public registry record.
Study Coordinator · 3126951301 · cancer@northwestern.edu
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| Northwestern University | Chicago, Illinois, United States | Recruiting |
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Source record: clinicaltrials.gov/study/NCT06723457