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Study identifier: NCT06722807 Synced from ClinicalTrials.gov · July 29, 2026
● Recruiting

ClAmpless, Sutureless PartIAl Nephrectomy for Renal Masses

Condition: Renal Cell Carcinoma (RCC)  ·  Sponsor: University of Florida

PhaseNA
Planned participants59
Who can joinAll sexes, 18 Years to no upper limit
Healthy volunteersNo

About this study

During partial nephrectomy surgery, efforts at minimizing ischemia while maximizing renal parenchymal volume are desirable to preserve renal function1,2. Not only clamping of the hilum but the renorrhaphy portion of the procedure also can have a significant negative impact on renal function3-5. It is possible to perform this procedure without clamping the hilum and also without formal renorrhaphy. However robust prospective formal evaluation of safety, risks, and potential benefits and whether or not the technique can be employed in a generalized fashion has not been studied. Demonstration of safety and generalizability may open a whole new avenue of approaching nephron sparing and renal function sparing kidney surgery and decrease potential risks for long term kidney disease in patients with renal masses. This study will investigate the safety, efficacy, and generalizability of the use of clampless, sutureless partial nephrectomy in the treatment of renal cell carcinoma.

This description comes directly from the study's public registry record.

Talk to the study team

Pravalika Manda  ·  (352) 265-9728  ·  pmanda@ufl.edu

Always discuss trial participation with your own doctor first.

Locations (1)

University of FloridaGainesville, Florida, United StatesRecruiting

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Source record: clinicaltrials.gov/study/NCT06722807