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Study identifier: NCT06722638 Synced from ClinicalTrials.gov · July 29, 2026
● Recruiting

Virtual Reality During Lumbar Punctures in Acute Lymphoblastic Leukemia

Condition: Acute Lymphoblastic Leukemia, Pediatric  ·  Sponsor: Children's National Research Institute

PhaseNA
Planned participants40
Who can joinAll sexes, 7 Years to no upper limit
Healthy volunteersNo

About this study

Over 90% of children and adolescents diagnosed with acute lymphoblastic leukemia (ALL) will survive long term. Part of the successful treatment that patients receive is the delivery of chemotherapy directly into their spinal fluid via a spinal tap. This takes place approximately 20 times over the course of treatment. Most children and adolescents receive general anesthesia during this procedure to manage pain and anxiety. It is now understood that general anesthesia contributes to impairments in brain functioning in the long term. Therefore, it is important to identify ways to manage pain and anxiety during these procedures that does not include general anesthesia. The investigators propose to test whether virtual reality (VR: a technology that provides immersive experiences utilizing content uploaded on a headset), used with local anesthesia and the option for an anti-anxiety medication will be an adequate replacement for general anesthesia for participants 7 years of age and over, with ALL in the maintenance phase of treatment.

This description comes directly from the study's public registry record.

Talk to the study team

Jennifer Levine, MD  ·  202-476-2140  ·  jlevine@childrensnational.org

Alissa Groisser, MD  ·  202-476-2140  ·  agroisser@childrensnational.org

Always discuss trial participation with your own doctor first.

Locations (1)

Children's National HospitalWashington D.C., District of Columbia, United StatesRecruiting

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Source record: clinicaltrials.gov/study/NCT06722638