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Study identifier: NCT06722482 Synced from ClinicalTrials.gov · July 28, 2026
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Comparison of Two Types of Bone Grafts in Patients Who Need One of Their Front Teeth Removed and Replaced With an Implant

Condition: Ridge Preservation · Allografts · Extraction, Tooth  ·  Sponsor: University of Rochester

PhaseNA
Planned participants50
Who can joinAll sexes, 18 Years to no upper limit
Healthy volunteersNo

About this study

The purpose of this study is to compare two different bone graft materials (freeze-dried bone allograft, FDBA and collagen-enriched bovine xenograft, CEBX) that are routinely used for preserving the remaining bone after extraction of an anterior tooth, and before placing a dental implant. Patients will be randomly assigned to either group (flip of a coin) One group will receive FDBA material and the other group will receive CEBX (cow) material. The study aims to examine the following main questions: * Potential differences in linear radiographic horizontal (HRD) and vertical (VRD) ridge dimensional changes between groups after 16 weeks of healing * Other clinical information of the treated areas and information regarding the esthetics of the dental implant that will subsequently be placed at the edentulous site as well as patient satisfaction with the treatment, will be evaluated. The study will include 7 study visits. Study procedures will take place during the same visits as the standard of care treatments (tooth extraction and bone graft, dental implant placement, crown installation and follow-ups). Clinical information from these standard of care visits will be used for the current research study, such as: * Demographic information * Clinical information from intraoral photographs * Radiographic information from cone beam computed tomography and periapical radiographs.

This description comes directly from the study's public registry record.

Talk to the study team

Elli Anna Kotsailidi, DDS, MS  ·  585-274-1146  ·  elli_kotsailidi@urmc.rochester.edu

Nasser Assery, BDS, MS  ·  nasser_assery@urmc.rochester.edu

Always discuss trial participation with your own doctor first.

Locations (1)

Eastman Institute for Oral HealthRochester, New York, United StatesRecruiting

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Source record: clinicaltrials.gov/study/NCT06722482