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Study identifier: NCT06719947 Synced from ClinicalTrials.gov · July 28, 2026
● Recruiting

HD-tDCS in Amyotrophic Lateral Sclerosis: A Multicenter Randomized Controlled Trial

Condition: Amyotrophic Lateral Sclerosis (ALS)  ·  Sponsor: Universidade Federal do Rio Grande do Norte

PhasePhase 2/Phase 3
Planned participants80
Who can joinAll sexes, 18 Years to 80 Years
Healthy volunteersNo

About this study

Amyotrophic Lateral Sclerosis (ALS) is a nervous system disease that causes muscle weakness and rapidly progresses to the loss of mobility and functionality. Studies suggest that High-Definition Transcranial Direct Current Stimulation (HD-tDCS) is a technique for modulating motor cortical hyperexcitability. However, evidence on the use of HD-tDCS as a neuromodulator of the diaphragmatic motor cortex in people with ALS is inconclusive.

This description comes directly from the study's public registry record.

Talk to the study team

Guilherme A. F Fregonezi, PhD  ·  +55(84)99426-7896  ·  guilherme.fregonezi@ufrn.br

Edna K. F Laurentino, MSc  ·  +55(84)99471-5172  ·  ednakarlaferreira@gmail.com

Always discuss trial participation with your own doctor first.

Locations (4)

Universidade de Brasília - Campus CeilândiaBrasília, Federal District, BrazilRecruiting
PneumoCardioVascular Lab - HUOL/UFRNNatal, Rio Grande do Norte, BrazilRecruiting
Universidad Autónoma de ChileSantiago, Santiago Metropolitan, ChileNot Yet Recruiting
Universidad do ChileSantiago, Santiago Metropolitan, ChileNot Yet Recruiting

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Source record: clinicaltrials.gov/study/NCT06719947