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Study identifier: NCT06718933 Synced from ClinicalTrials.gov · July 28, 2026
● Recruiting

Study of SHR-A1811 Combined With Pyrotinib and Bevacizumab in Advanced Breast Cancer With Brain Metastasis

Condition: Breast Cancer Metastatic · Breast Cancer Brain Metastases  ·  Sponsor: Fudan University

PhasePhase 1/Phase 2
Planned participants74
Who can joinAll sexes, 18 Years to no upper limit
Healthy volunteersNo

About this study

In phase Ib, our study is aimed to evaluate the safety and tolerance of SHR-A1811 combined with pyrotinib in breast cancer with brain metastasis, and confirm the recommended phase 2 dose combined with preliminary results of efficacy. In phase II, our study is aimed to evaluate the efficacy and safety of SHR-A1811 combined with pyrotinib and bevacizumab at RP2D in breast cancer with brain metastasis.

This description comes directly from the study's public registry record.

Talk to the study team

Hongxia Wang, Chief physician  ·  +8621-38196379  ·  whx365@126.com

Ting Li, Associate chief physician  ·  +86-18121299346  ·  cinderellaliting@126.com

Always discuss trial participation with your own doctor first.

Locations (1)

Fudan Cancer HospitalShanghai, Shanghai Municipality, ChinaRecruiting

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Source record: clinicaltrials.gov/study/NCT06718933