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Study identifier: NCT06718543 Synced from ClinicalTrials.gov · July 28, 2026
● Recruiting

Neoadjuvant Short-Course Radiotherapy With or Without Chemotherapy and AK112 in Locally Advanced Rectal Cancer

Condition: Rectal Cancer  ·  Sponsor: fan li

PhasePhase 2
Planned participants100
Who can joinAll sexes, 18 Years to 80 Years
Healthy volunteersNo

About this study

This phase II multicenter, randomized study evaluates the safety and efficacy of neoadjuvant short-course radiotherapy (SCRT) sequentially combined with AK112 (Envafolimab) with or without chemotherapy in patients with locally advanced rectal cancer (LARC). The study also aims to identify biomarkers predicting tumor response and develop efficacy prediction models.

This description comes directly from the study's public registry record.

Talk to the study team

Fan LI, PhD  ·  +8618696539200  ·  levinecq@163.com

Haode Shen, MD  ·  +8617783437391  ·  imshd@qq.com

Always discuss trial participation with your own doctor first.

Locations (1)

Daping HospitalChongqing, Chongqing Municipality, ChinaRecruiting

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Source record: clinicaltrials.gov/study/NCT06718543