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Study identifier: NCT06716606 Synced from ClinicalTrials.gov · July 29, 2026
● Recruiting

A Study to Investigate the Long-term Safety and Efficacy of Belimumab in Adults With Interstitial Lung Disease (ILD) Associated With Systemic Sclerosis (SSc) and Other Connective Tissue Diseases (CTD) (BLISSconneCTD-OLE)

Condition: Connective Tissue Diseases  ·  Sponsor: GlaxoSmithKline

PhasePhase 3
Planned participants514
Who can joinAll sexes, 18 Years to no upper limit
Healthy volunteersNo

About this study

This is an open label extension (OLE) study of an ongoing randomized controlled parent clinical studies 218224 (NCT05878717) and 221672 (NCT06572384) which aim to assess the efficacy and safety of belimumab on reducing the decline in lung function in participants with interstitial lung disease associated with diffuse cutaneous systemic sclerosis (dcSSc-ILD) and interstitial lung disease associated with other connective tissue diseases (CTD-ILD), respectively. The OLE study will describe how well tolerated belimumab will be long term, and whether it might continue to slow progression of lung function decline, slow overall disease progression and improve quality of life.

This description comes directly from the study's public registry record.

Talk to the study team

US GSK Clinical Trials Call Center  ·  877-379-3718  ·  GSKClinicalSupportHD@gsk.com

EU GSK Clinical Trials Call Center  ·  +44 (0) 20 89904466  ·  GSKClinicalSupportHD@gsk.com

Always discuss trial participation with your own doctor first.

Locations (10)

GSK Investigational SitePhiladelphia, Pennsylvania, United StatesRecruiting
GSK Investigational SiteCiudad Autonoma Buenos Aires, ArgentinaRecruiting
GSK Investigational SiteCiudad Autonoma de Buenos Aire, ArgentinaRecruiting
GSK Investigational SiteBeijing, ChinaRecruiting
GSK Investigational SiteZhuzhou, ChinaRecruiting
GSK Investigational SiteLarissa, GreeceRecruiting
GSK Investigational SiteHokkaido, JapanRecruiting
GSK Investigational SiteTokyo, JapanRecruiting
GSK Investigational SiteYongsan-Ku Seoul, South KoreaRecruiting
GSK Investigational SiteLondon, United KingdomRecruiting

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Source record: clinicaltrials.gov/study/NCT06716606