Condition: Stroke, Ischemic · Small Vessel Cerebrovascular Disease · White Matter Hyperintensity · Sponsor: The First Affiliated Hospital with Nanjing Medical University
Cerebral small vessel disease (cSVD) is a common accompaniment of aging. Recent small subcortical (or lacunar) infarcts (i.e. symptomatic cSVD) and white matter hyperintensities are typical cSVD lesions on neuroimaging. cSVD causes about a quarter of ischaemic strokes and related with cognitive dysfunction. However, few studies are available so far to especially explore the treatment of cSVD. Endothelial dysfunction plays an important part in cSVD. Cilostazol and isosorbide mononitrate have endothelial protective function. We designed this prospective cohort study in China, aiming to evaluate the effect of different antiplatelet agents (e.g. Cilostazol) on cSVD and retina in patients with cSVD (recent small subcortical infarcts or WMH, respectively).
This description comes directly from the study's public registry record.
Zhaolu Wang, MD · +86 18100613663 · wangzhaolu123@163.com
Xinyu Chen · njmuchenxinyu@163.com
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| the First affiliated hospital of Nanjing Medical University | Nanjing, Jiangsu, China | Recruiting |
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Source record: clinicaltrials.gov/study/NCT06715007