Condition: Chronic Obstructive Lung Disease · Respiratory Ilness · Estrogen Deficiency · Sponsor: Guy's and St Thomas' NHS Foundation Trust
This study aims to understand the role of oestrogen in patients with asthma and Chronic Obstructive Pulmonary Disorder (COPD). Therefore, what is the effect of oestrogen in these participants compared to controls (those without disease). The study hypothesises that oestrogen loss in patients with asthma and COPD causes accelerated lung function decline and changes to lung structure. It will investigate if this is mediated by inflammation, immune host response or elastin and collagen changes. It is an observational prospective cohort study aiming to recruit healthy controls, and people with asthma or COPD), and/or the menopause.
This description comes directly from the study's public registry record.
Gill Radcliffe Ms, MRes · +442071888070 · gillian.radcliffe@gstt.nhs.uk
Chris Mwasuku · Christine.Mwasuku@gstt.nhs.uk
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| Guys & St Thomas NHS Foundation Trust | London, United Kingdom | Recruiting |
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Source record: clinicaltrials.gov/study/NCT06713512