Condition: Locally Advanced or Metastatic Solid Tumor · Sponsor: AstraZeneca
This Phase I, open-label study aims to study to absolute bioavailability of Saruparib (AZD5305) and the absorption, distribution, metabolism and excretion (ADME) of \[14C\]-Saruparib in patients with advanced solid malignancies. This will be done on an inpatient basis in 2 parts (single-dose oral administration with radiolabeled microtracer in Part A, single-dose IV radiolabeled administration in Part B) during which samples will be obtained of plasma, urine, feces and vomitus (where applicable).
This description comes directly from the study's public registry record.
AstraZeneca Clinical Study Information Center · 1-877-240-9479 · information.center@astrazeneca.com
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| Research Site | Liverpool, United Kingdom | Recruiting |
| Research Site | Manchester, United Kingdom | Recruiting |
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Source record: clinicaltrials.gov/study/NCT06713369