Condition: Amblyopia · Sponsor: Midwestern University
The goal of this randomized controlled trial is to investigate the effectiveness of non-invasive brain stimulation in treating adults with amblyopia. The main questions it aims to answer are: 1. What are the effects of non-invasive brain stimulation on neuronal plasticity in the visual cortex of adults with amblyopia, and does it produce lasting changes? 2. Do cumulative sessions of non-invasive brain stimulation influence neural plasticity and higher-order visual functions in adults with amblyopia? The investigators hypothesize that non-invasive brain stimulation will show a positive cumulative effect after five (5) consecutive days of stimulation on visual perception and function in adults with amblyopia. Participants will be randomized into one of two treatment groups: 1. High-frequency transcranial random noise stimulation (hf-tRNS). 2. Sham stimulation. Researchers will compare baseline measurements of crowded visual acuity, contrast sensitivity, stereoacuity, phosphene thresholds, global motion perception, form pattern recognition and pattern-reversal visual evoked potentials (VEPs) to post-treatment measurements for each group.
This description comes directly from the study's public registry record.
Arijit Chakraborty, PhD · 630-960-3172 · achakr@midwestern.edu
Adrienne C Quan, OD · 630-960-3183 · aquan@midwestern.edu
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| Midwestern University Eye Institute | Downers Grove, Illinois, United States | Recruiting |
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Source record: clinicaltrials.gov/study/NCT06712849