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Study identifier: NCT06712849 Synced from ClinicalTrials.gov · July 28, 2026
● Recruiting

Noninvasive Brain Stimulation in Adult Amblyopia

Condition: Amblyopia  ·  Sponsor: Midwestern University

PhaseNA
Planned participants60
Who can joinAll sexes, 18 Years to 55 Years
Healthy volunteersYes

About this study

The goal of this randomized controlled trial is to investigate the effectiveness of non-invasive brain stimulation in treating adults with amblyopia. The main questions it aims to answer are: 1. What are the effects of non-invasive brain stimulation on neuronal plasticity in the visual cortex of adults with amblyopia, and does it produce lasting changes? 2. Do cumulative sessions of non-invasive brain stimulation influence neural plasticity and higher-order visual functions in adults with amblyopia? The investigators hypothesize that non-invasive brain stimulation will show a positive cumulative effect after five (5) consecutive days of stimulation on visual perception and function in adults with amblyopia. Participants will be randomized into one of two treatment groups: 1. High-frequency transcranial random noise stimulation (hf-tRNS). 2. Sham stimulation. Researchers will compare baseline measurements of crowded visual acuity, contrast sensitivity, stereoacuity, phosphene thresholds, global motion perception, form pattern recognition and pattern-reversal visual evoked potentials (VEPs) to post-treatment measurements for each group.

This description comes directly from the study's public registry record.

Talk to the study team

Arijit Chakraborty, PhD  ·  630-960-3172  ·  achakr@midwestern.edu

Adrienne C Quan, OD  ·  630-960-3183  ·  aquan@midwestern.edu

Always discuss trial participation with your own doctor first.

Locations (1)

Midwestern University Eye InstituteDowners Grove, Illinois, United StatesRecruiting

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Source record: clinicaltrials.gov/study/NCT06712849