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Study identifier: NCT06712316 Synced from ClinicalTrials.gov · July 28, 2026
● Recruiting

Safety, Efficacy, and Pharmacokinetics of BNT327 in Combination With Chemotherapy and Other Investigational Agents for Lung Cancer

Condition: Non-small Cell Lung Cancer  ·  Sponsor: BioNTech SE

PhasePhase 2/Phase 3
Planned participants1260
Who can joinAll sexes, 18 Years to no upper limit
Healthy volunteersNo

About this study

This is a Phase 2/3, multisite, randomized, open-label study in participants with first-line non-small cell lung cancer (NSCLC). This study includes two substudies (substudy A and substudy B) that will recruit participants according to histological subtypes due to differences in chemotherapy choice for standard-of-care and type of NSCLC.

This description comes directly from the study's public registry record.

Talk to the study team

BioNTech clinical trials patient information  ·  +49 6131 9084  ·  patients@biontech.de

Always discuss trial participation with your own doctor first.

Locations (261)

Birmingham Hematology and Oncology Associates LLC d/b/a Alabama OncologyBirmingham, Alabama, United StatesRecruiting
Alaska Oncology and Hematology, LLCAnchorage, Alaska, United StatesRecruiting
John Muir Clinical Research CenterConcord, California, United StatesRecruiting
University Of California - San Diego Moores Cancer CenterLa Jolla, California, United StatesRecruiting
Clermont Oncology CenterClermont, Florida, United StatesRecruiting
Mid Florida Cancer CentersOrange City, Florida, United StatesRecruiting
Cleveland Clinic Florida - Martin North HospitalStuart, Florida, United StatesRecruiting
H. Lee Moffit Cancer center and research instituteTampa, Florida, United StatesRecruiting
Cleveland Clinic Weston HospitalWeston, Florida, United StatesRecruiting
Fort Wayne Medical Oncology and Hematology, Inc.Fort Wayne, Indiana, United StatesRecruiting
Physicians Clinic of IowaCedar Rapids, Iowa, United StatesRecruiting
Holden Comprehensive Cancer Center, University of Iowa Hospitals and ClinicsIowa City, Iowa, United StatesRecruiting

+ 249 more locations — full list on the registry record.

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Source record: clinicaltrials.gov/study/NCT06712316