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Study identifier: NCT06709963 Synced from ClinicalTrials.gov · July 29, 2026
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The Effect of Intermittent Theta Burst Stimulation on Brain Characteristics, Pain Intensity, and Cognitive Functions in Older People with Chronic Musculoskeletal Pain.

Condition: Chronic Non-Specific Low Back Pain · Chronic Knee Pain · Chronic Musculoskeletal Pain  ·  Sponsor: The Hong Kong Polytechnic University

PhaseNA
Planned participants30
Who can joinAll sexes, 60 Years to 85 Years
Healthy volunteersNo

About this study

The goal of this clinical trial is to explore the effects of accelerated intermittent Theta Burst Stimulation (iTBS) on pain relief and cognitive function in older adults with chronic musculoskeletal pain. It will also utilize magnetic resonance imaging to illustrate the neurophysiological mechanisms underlying the role of iTBS in improving various outcome indicators in this population. The main questions it aims to answer are: 1. Is left dorsolateral prefrontal cortex stimulation using accelerated iTBS effective for older adults with chronic musculoskeletal pain? 2. What are the neurophysiological mechanisms underlying the role of iTBS in improving various outcome indicators in older adults with chronic musculoskeletal pain? Participants will: 1. Receive 1,200 stimuli during a single-session iTBS, totaling 14 days. 2. Undergo MRI scanning before, immediately after treatment, cognitive and pain-related tests before, immediately after treatment, and during follow-up.

This description comes directly from the study's public registry record.

Talk to the study team

Fan Dr. Huang  ·  +852 5303 7752  ·  fan2023.huang@connect.polyu.hk

Yat Ching Miss Wong  ·  +852 60799195  ·  yatching.wong@connect.polyu.hk

Always discuss trial participation with your own doctor first.

Locations (1)

The Hong Kong Polytechnic UniversityHong Kong, Hong KongRecruiting

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Source record: clinicaltrials.gov/study/NCT06709963