Condition: Triple Negative Breast Cancer · Sponsor: University College Cork
Predictive biomarkers of response to combination chemotherapy and immune-checkpoint inhibitors are urgently needed to help tailor treatment recommendations for patients with early-stage TNBC. Tumour-associated microbiota in primary breast tumours represent promising and novel candidate biomarkers modulators of the efficacy of therapies for patients with TNBC. It has been shown that microbes colonizing breast tumours can modulate the efficacy of commonly used drugs and that the microbiome of breast tissue biopsies could represent a new biomarker. Data on the microbiome of patients with cancer indicate the potential for a new class of bacteria-based oncological biomarkers, for exploitation in precision oncology.
This description comes directly from the study's public registry record.
Roisin Connolly · 021 4922687 · roisin.connolly@ucc.ie
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| Cork University Hospital | Cork, Munster, Ireland | Recruiting |
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Source record: clinicaltrials.gov/study/NCT06709651