Condition: Precursor Cell Lymphoblastic Leukemia-Lymphoma · Sponsor: Instituto de Investigación Hospital Universitario La Paz
The goal of this clinical trial is to test the feasibility and safety of an academic production of two different anti-CD19 chimeric antigen receptor T cells (CART) products according to the different biomarkers of the disease in children and young adults with relapsed/refractory CD19+ B cell acute lymphoblastic leukemia (r/r B-ALL) or relapsed/refractory T-cell acute lymphoblastic leukemia (r/r T-ALL). The main questions it aims to answer are: 1. The safety and feasibility of autologous CART-19/22 in children, adolescents and young adults with a CD19+/- CD22+ relapse/ refractory disease for a r/r B-ALL. 2. The safety and feasibility of allogeneic CART-NKG2D (chimeric-antigen receptor Natural-killer group 2, member D) in children, adolescents and young adults with r/r T-ALL.
This description comes directly from the study's public registry record.
Antonio Pérez Martínez, MD · 917 27 75 76 · aperezmartinez@salud.madrid.org
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| Hospital Universitario La Paz | Madrid, Madrid, Spain | Recruiting |
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Source record: clinicaltrials.gov/study/NCT06709469