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Study identifier: NCT06709417 Synced from ClinicalTrials.gov · July 28, 2026
● Recruiting

A Phase II Clinical Study of Sintilimab Combined with Chemotherapy Followed by Concurrent Chemoradiotherapy for Locally Advanced Unresectable Esophageal Squamous Cell Carcinoma (ESCC) (NICE-CS)

Condition: Esophageal Squamous Cell Carcinoma (ESCC)  ·  Sponsor: Shanghai Chest Hospital

PhasePhase 2
Planned participants52
Who can joinAll sexes, 20 Years to 75 Years
Healthy volunteersNo

About this study

This is a prospective, single-arm, phase II clinical study designed to evaluate the efficacy and safety of sintilimab combined with chemotherapy, followed by sequential concurrent chemoradiotherapy as conversion therapy, in treatment-naïve esophageal squamous cell carcinoma (ESCC) patients with cT4bN-/+M0 and/or cTanyN+M0 staging (including those with extracapsular invasion of mediastinal lymph nodes).

This description comes directly from the study's public registry record.

Talk to the study team

Jun Liu  ·  +862122200000  ·  drjunliu@qq.com

Always discuss trial participation with your own doctor first.

Locations (1)

Shanghai Chest HospitalShanghai, Shanghai Municipality, ChinaRecruiting

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Source record: clinicaltrials.gov/study/NCT06709417